SKU: 6591556221

Natural Factors Acetyl-L-Carnitine 500mg - 60 Capsules

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Description

Natural Factors Acetyl-L-Carnitine 500mg - 60 CapsulesProduct Information Carnitine and its derivatives exist in a carnitine pool in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl L carnitine (ALC) is the most important derivative of carnitine and

Product Information

Carnitine and its derivatives exist in a carnitine “pool” in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl-L-carnitine (ALC) is the most important derivative of carnitine and occurs naturally in the body. Because ALC is considered to have greater bioavailability and is therefore more able to cross neurological membranes, it is the preferred form to take for promoting neurological health. 

The levels of carnitine and its derivatives are critical to normal biological functioning. Carnitine is present in the diet in red meats and dairy products, and humans can make carnitine from the amino acids lysine and methionine. However, carnitine deficiency can occur with metabolic disorders, and in conditions such as diabetic neuropathy (nerve pain) and other complications of diabetes. 

ALC has been studied in various conditions including neurological and cognitive disorders such as Alzheimer’s, dementia, depression, neuropathies, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica.

Main selling features

  • The most important derivative of carnitine, and the preferred form to take, as it is the most bioavailable
  • Able to cross the blood-brain barrier
  • Has many neurological benefits, including cognitive ability, memory, and mood
  • Naturally occurring nutrient, free from toxic effects

How it works

Acetyl-L-carnitine is the most abundant naturally occurring derivative of carnitine. ALC helps the body produce energy at the cellular level; regulates carbohydrate, lipid and protein metabolism; facilitates fatty acid entry into the mitochondria; and maintains the homeostasis of coenzyme A. ALC also displays potent antioxidant effects and supports repair mechanisms. ALC has been shown to support heart and brain function, muscle movement, and numerous other body processes. 

ALC protects and enhances the activity of neurons and transmitters in the mitochondria and reduces oxidative stress. By improving cellular function and effi ciency in the mitochondria, ALC stabilizes the fl uidity and function of cell membranes, and improves energy production. ALC is involved in peripheral nerve regeneration and has shown promise in improving neuropathy. Because ALC is able to cross the blood-brain barrier it is able to exert its neuroprotective effects in the brain. Studies have shown ALC can improve cognitive performance and mood by protecting against oxidative stress and reducing or blocking the neuronal death that occurs with dementia and other neurodegenerative conditions. 

Supplementation with ALC may be useful in a broad range of conditions, including Alzheimer’s, dementia, age-related memory loss and depression, fatigue, diabetic neuropathy, and cardiovascular disease.

Positioning Line

Boosts physical and mental energy

Ingredients
Each Capsule Contains:  
Acetyl-L-Carnitine 
(N-Acetyl L-carnitine hydrochloride)
500 mg

Non-Medicinal ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.  

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SKU: 6591556221

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4.4 ★★★★★
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ShelbbLC
West Palm Beach, US
★★★★★ 3
Love the sheets but GOSH THEY STINK
Color: 19 - Forest Green, Size: Queen (20" X 30")
I have the dark green sheets and bought these for extra cases to match. I would give them 5 stars if it weren’t for the fact that they smell absolutely horrible. I am so surprised after reading reviews that more people don’t mention it?! Maybe it’s more prominent in darker colors but I have washed these now 3 different times even with scent beads and still hate the smell. I wish I could accurately describe what it smells like— it’s just not good and for some reason, body heat only exacerbates it and makes the smell even worse and I wake up feeling like a smell like the sheets… which isn’t a good thing. Besides that, I do really enjoy them. They feel great on your skin and I love the color. I wish the smell didn’t kill them so badly for me ☹️
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 9, 2026
A
Verified Purchase
Amy
Houston, US
★★★★★ 5
Comfy soft pillow covers
Color: 02 - White, Size: Queen (20" X 30"), Color: 02 - White, Size: Queen (20" X 30")
Absolutely love these pillow cases! I bought 2 sets. After I received them & washed & dried them they did remain wrinkly. I just went ahead and put them on my pillows & the wrinkles went away. I continue to love the feel, coolness & comfort. Will definitely buy more.
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Reviewed in the United States on April 5, 2026
L
Verified Purchase
Lisa Brown
Charlottesville, US
★★★★★ 5
Great soft pillow cases
Color: 03 - Navy, Size: Standard (20" X 26")
Pillow cases are beautiful and soft, great quality. I had to return them because standard were too small. I am going to order queen instead.
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Reviewed in the United States on June 9, 2026
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Verified Purchase
Precise Disarray
Battle Creek, US
★★★★★ 5
super smooth, silky, stays comfortable feeling. DO NOT DRY or wash with heat
Color: Blue, Size: Queen (U.S. Standard), Set name: Stretchy and Soft, Color: Blue, Size: Queen (U.S. Standard), Set name: Stretchy and Soft
I'm impressed. I have used cooling pillow cases before, and found them effective, but the cooling material have always been on just one side. These are 100% cooling material. The material is super smooth and silky feeling. It is great feeling against hair and skin (even better than my old polyester satin I was using before cooling pillowcases). The material is cool, and does not seem to get hot hot. The pillow cases are super stretchy with a small hidden zipper. They grab onto the pillow and dont loosen up. Makes my pillow look neat and clean, not sloppy from loose material. I can even have two pillows stacked and somehow despite being a smooth material, the pillows dont just slide off each other. The cooling aspect works by not trapping heat, not allowing heat to get to the pillow and hold it there. So yeh, the pillow case will feel warm eventually but if you have a fan, or AC, or flip the pillow, then it is is truly cool. Otherwise in my experience when I use a pillow without this, the pillow just gets hot, stays hot, and even with flipping it feels hot.. because the pillow itself has trapped the heat for remainder of night. Yuck. One thing to know and this is very important-- as I learned the hard way-- DO NOT DRY IN DRYER. DO NOT WASH IN HOT WATER. Heat will destroy the material ability to feel and stay cool. Do you want a regular heat trapping pillow case? Then go ahead and dry these in the dryer a few times and you will have a regular pillow case. HOw do I know? I bought these to replace another set (different brand, same idea, same instructions that I failed to remember). I always dried them in the dryer, and one night after having gloriously cool pillows, I noticed that my pillow was HOT night after night. It was then when looking for another set of pillow cases that I learned that they cant be exposed to heat like that. SO PLEASE, just AIR DRY. And so, after I got these and put them on my pillows, I had a much better nights rest. I remember thinking that I wasnt waking to rearrange my pillows. They were just comfortable all night long. Sure, I'd love an even colder pillow, but our room is on the warm side. But at least I wasnt noting the hot hot pillows anymore.
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Reviewed in the United States on June 6, 2021
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Verified Purchase
Grace
Pawtucket, US
★★★★★ 5
A must try for hot sleepers!
Color: Blue, Size: Queen (U.S. Standard), Set name: Silky, Color: Blue, Size: Queen (U.S. Standard), Set name: Silky
If you are a hot sleeper these pillowcases are for you! Not only are they silky and beautiful, but they are cool to the touch!The Arc-Chill fabric absorbs heat and instantly cools your skin! If you are prone to insomnia, night sweats, give these a try! They come in a 2 pack and have a few different colors to try out. Highly recommend.
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Reviewed in the United States on May 27, 2026

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