SKU: 92985954725

프로맥정 Acute gastric ulcer, chronic gastric inflammation

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Description

프로맥정 Acute gastric ulcer, chronic gastric inflammation1(150. 0mg) 75. 0mg 1. 2. (, , , ) : , 1 75mg (1) 1 2 . 100T , (1~30) 36 1. 1) , ( ): AST, ALT, GTP, ALP , . ( ): . . 2) : . 0. 1~1% () 0. 1% () * , , , AST, ALT, ALP, LDH, GTP , , , , * . 3) 373 , , . 4) (1) 6 3,588 , 1. 48%(53 3,588, 60) . 0. 25%(9 3,588, 10) 0. 03%(1 3,588, 2), , , , , , , , 0. 03%(1 3,588, 1) , . 0. 98%(35 3,588, 38) , 0. 08% (3 3,588, 3), , , , 0. 06% (2 3,588, 2), 0. 03%(1 3,588, 2), , , , , , , , , , , , , , , , , , , , , , , ,

성분정보

이 약 1정(150.0mg) 중
폴라프레징크 75.0mg

효능효과

1. 위궤양

2. 다음 질환의 위점막병변(미란, 출혈, 발적, 부종)의 개선:
급성위염, 만성위염의 급성악화기

용법용량

보통 성인은 폴라프레징크로서 1회 75mg (1정)을 1일 2회 아침식사후 및 취침전에 경구투여한다.

포장단위

100T

저장방법

기밀용기, 실온(1~30℃) 보관

사용기간

제조일로부터 36 개월

사용상주의사항

1. 이상반응
1) 중대한 이상반응
간기능장애, 황달(빈도 불명): AST, ALT, γ-GTP, ALP 상승 등의 간기능장애, 황달이 나타날 수 있으므로 이상이 인정되는 경우에는 즉시 투여를 중지하고 적절한 처치를 한다.
구리결핍(빈도 불명): 폴라프레징크는 구리의 흡수를 방해하는 아연을 함유하므로 구리결핍이 나타날 수 있다. 영양 부족 환자에서 구리결핍으로 인한 범혈구감소증 및 빈혈이 보고되었으므로 이상이 인정되는 경우에는 적절한 처치를 한다.
2) 기타 이상반응: 다음 이상반응이 확인된 경우에는 증상에 대해 적절한 처치를 한다.

 

발현빈도

기관계

 

 

0.1~1% 미만

(때때로)

 

 

0.1% 미만

(드물게)

 

빈도불명

과민증*

 

발진, 가려움증

두드러기

혈액계

호산구증가, 백혈구감소, 혈소판감소

 

 

간장

AST상승, ALT상승, ALP상승, LDH상승, γ-GTP상승

 

 

소화기계

변비, 구역, 복부팽만감

구토, 속쓰림, 설사

 


* 과민증이 나타날 경우에는 투여를 중지한다.
3) 국내 임상시험을 통해 373명의 환자에 대한 안전성을 평가한 결과, 이 약을 투여받은 환자들에서 보고된 가장 흔한 이상반응은 구역, 소화불량이었다.
4) 국내 시판 후 조사결과
(1) 국내에서 재심사를 위하여 6년 동안 3,588명을 대상으로 실시한 시판 후 조사 결과, 이상사례의 발현율은 인과관계와 상관없이 1.48%(53/3,588명, 총 60건)로 보고되었다. 이 중 중대한 이상사례의 발현율은 0.25%(9/3,588명, 10건)로 뇌경색 0.03%(1/3,588명, 2건), 경련, 경막하출혈, 식도암종, 아밀로이드증, 요관결석, 잇몸출혈, 척추관협착, 췌장염악화가 각 0.03%(1/3,588명, 1건)로 보고되었으며, 이 약과 인과관계를 배제할 수 없는 중대한 약물이상반응은 보고되지 않았다. 예상하지 못한 이상사례의 발현율은 인과관계와 상관없이 0.98%(35/3,588명, 총 38건)로 보고되었으며, 보고된 예상하지 못한 이상사례는 기침 0.08% (3/3,588명, 3건), 가슴통증, 근육통, 식욕부진, 어지러움 각 0.06% (2/3,588명, 2건), 뇌경색 0.03%(1/3,588명, 2건), 가래질환, 감기, 경련, 경막하출혈, 두통, 목긴장, 백내장, 복부불편감, 부종, 사위, 상기도감염, 식도암종, 아밀로이드증, 얼굴부종, 요관결석, 인후통, 잇몸출혈, 위식도역류, 전신부종, 척추관협착, 췌장염악화, 코감기, 콧물, 폐질환, 홍반성 발진 각 0.03% (1/3,588명, 1건)로 조사되었다. 이 중 이 약과 인과관계를 배제할 수 없는 예상하지 못한 약물이상반응 발현율은 0.06%(2/3,588명, 총 2건)로 백내장, 사위 각 0.03% (1/3,588명, 1건)이 보고되었다.
(2) 이 약에 대한 국내 재심사이상사례 및 자발적 부작용 보고자료를 국내 시판 허가된 모든 의약품을 대상으로 보고된 이상사례 보고자료와 재심사 종료시점에서 통합평가한 결과, 다른 모든 의약품에서 보고된 이상사례에 비해 이 약에서 통계적으로 유의하게 많이 보고된 이상사례 중 새로 확인된 것들은 다음과 같다. 다만, 이 결과가 해당성분과 다음의 이상사례간에 인과관계가 입증된 것을 의미하는 것은 아니다.
● 위장관계 장애 : 복통

2. 상호작용
페니실라민, 레보티록신나트륨과 함께 복용 시 병용약제의 효과가 감소될 우려가 있으므로 부득이 투여해야 할 경우에는 동시에 복용하지 않는 등 주의해서 투여한다.

3. 임부ㆍ수유부에 대한 투여
1) 임신중의 투여에 관한 안전성은 확립되어 있지 않으므로 임부 또는 임신하고 있을 가능성이 있는 부인에게는 치료상의 유익성이 위험성을 상회한다고 판단되는 경우에만 투여한다.
2) 동물실험에서 모유중으로 이행하는 것이 보고되어 있으므로 수유부에게 투여하는 경우에는 수유를 피한다.

4. 소아에 대한 투여
소아에 대한 안전성은 확립되어 있지 않다.(사용경험이 없다.)

5. 고령자에 대한 투여
일반적으로 고령자는 소화기 기능이 저하되어 있으므로, 감량(1일 100mg)하는 등 환자의 상태를 관찰하면서 투여하도록 한다.

6. 보관 및 취급상의 주의사항
1) 소아의 손이 닿지 않는 곳에 보관한다.
2) 오용을 막고 품질의 보존을 위하여 다른 용기에 바꾸어 넣지 않는다.

 

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SKU: 92985954725

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4.8 ★★★★★
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Niz
Cuba, US
★★★★★ 5
Has me feeling prepared
Format: Paperback
Gearing up to hike the first section of the PCT. I got this book, my hiking buddy got a different book that covers the entire trail. While talking about our hiking plans he often says “my book didn’t mention that.” It’s clear this book is more detailed and up to date. I’m feeling very prepared and in the know about what to expect on the PCT.
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Reviewed in the United States on May 1, 2021
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Verified Purchase
Fritz R. Ward
West Palm Beach, US
★★★★★ 4
The Best of the Modern Guides to the PCT.
Format: Paperback
This book is not an update of the Wilderness Press classics on which the trail was discovered and hiked by a couple generations from the 1970s to around 2010. It does however owe those books a heavy and unacknowledged debt. This is most notable in lettering sections which the author of this guide, Shawnte Salabert, attributes to the PCTA but in fact come from scarified, Schaffer, et all who wrote the original guides to California, Oregon, and Washington. Even the definition of sweat constitutes the Southern California trail, comes from those guides. (It starts at the Mexican Border near Campo California and ends in Tuolumne Meadows, Yosemite.). But alas, those books are long out of print, in part because today’s hikers prefer light weight apps with minimal trail information as opposed to detailed descriptions of the physical geography and varied ecosystems of the trail. I’m not sure the lost knowledge has equaled the reduced weight but I’m a bit old school. And this book is as much a throwback to that kind of writing as it is a nod to recent demands of the hiking community. It does cover every mile of the route, suggest campsites along the way, and as much as possible provide an option for day and section hikes along the trail for just about anyone. The author provides good car descriptions to major trailheads for each section hike he recommends as well as available entry and exit options along the way. The writing is entertaining and the author has his own sense of humor that will become readily apparent as you read the text. Based on my experiences (and I’ve hiked 95% of the trail he describes at least once; sometimes multiple times) his mileage descriptions are accurate and you will easily be able to recognize the places he describes along the way. The book also features nice color photos and it’s availability in digital form will certainly please the gram counting hiker set. On the other hand, I miss seeing elevations along with miles at each major trail intersection, pass etc. Salabert does give total elevation gain and loss for each section of trail he describes but sometimes it’s nice to know just how much of a climb to expect. Ultimately, this book fulfills it’s purpose. You should want to hike the PCT after reading a few pages if you hadn’t already when you purchased the book. And if you are like many people with only a weekend or a few days to spare hiking the trail, this book will make planning short sections easier. It offers a lot. But it reminds me of an era when guidebooks offered even more.
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Reviewed in the United States on June 17, 2020
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Darrow Kirkpatrick
Alexandria, US
★★★★★ 5
Superb Guide in All Respects
Format: Paperback
An invaluable reference for anybody interested in section hiking the trail. I especially appreciate the coverage of water and campsites. It’s also a fun and beautiful read for any armchair adventurer. Salabert did an amazing job bringing together well-written text, data, maps, and beautiful photos to create a comprehensive guidebook. Deserves to do very well.
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Reviewed in the United States on February 6, 2018
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Paul C Heidrick
Lake Worth, US
★★★★★ 5
Very good comprehensive collection of Section Hikes of the PCT
Format: Paperback
Great Maps. Accurate descriptions of everything (verified on previous hikes and hikes using the book).Well organized and beautifully laid out.
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Reviewed in the United States on August 28, 2021
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Dan Morris
Alexandria, US
★★★★★ 5
Truly embracing life along the Camino de Santiago
Format: Paperback, Format: Paperback
The Way of the Wind: Embracing Life While Walking the Camino do Santiago, by John W. Pearson, 2021, recounts one man’s experiences while walking the Camino de Santiago, a thirty-five day, five hundred mile walking journey from St. Jean Pied de Port in France to Santiago de Compostela in Spain. The journey follows a path tread by literally millions of pilgrims, or “pelegrinos”, as they seek to find something very person in the experience. The book is a travelogue recounting the miles of the daily trek, the people, stories, dining, lodging, and local services encountered along the way. There are a series of black and white photographs accenting the dialogue which give the reader a sense of involvement in the story. A nice touch was a simple map at the beginning to orient the reader along each day’s travel. I absolutely loved this book. It was enjoyable to read and I found myself slowing down near the end of the book to better savor the details. It warrants a double read to go back and let those early experiences soak in a bit more. I found the book to be educational, as I learned a lot about the historical significance of the route of the Camino, as well as specific landmarks along the way, such as a 10th century Roman bridge dwarfed by a new modern bridge overhead. I imagined myself walking along that ancient roadway, imagining what a pilgrim in 1300 must have thought. The dialogue is playful, recount with hours of walking, lively dinners, and crowded “albergues” (think camp dorm rooms with bunk beds). All was not rosy along the Camino. The narrative relates the aches of sore feet, legs, backs; the challenges of securing lodging and laundry; meanings lost in translation; inclement weather and treacherous roadways. Often mentioned are markers to honor the fallen dead along the Camino. About 2/3rds through the book, John recants his very personal reason for going on the pilgrimage, which he describes as “The Whale in the Room”, referring to the motivation of Captain Ahab in Moby Dick. His honesty and vulnerability bring the entire journey into focus. He brings the reader to the Cruz de Ferro, where pilgrims have stopped for millennium with their deepest meanings. I have known John Pearson since 1975, when we met in High School in El Paso, Texas. However, through the years, I moved and we lost close touch. There were many parts of this book of which I did not know the details. John’s story is very powerful, and will impact the reader deeply. Once you have read the book, you will have a clear idea of the experience, and can judge for yourself if the Camino de Santiago is calling you. For me, I found the book asking me not “WILL you go?”, but “WHEN will you go?”
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Reviewed in the United States on May 9, 2021

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