HLA-G Recombinant Rabbit mAb (S-2711-78)
SKU: 50453321647

HLA-G Recombinant Rabbit mAb (S-2711-78)

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Description

HLA-G Recombinant Rabbit mAb (S-2711-78)Product Specification Host Rabbit Antigen HLA G Synonyms HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; MHC class I antigen G; HLA 6. 0; HLAG Immunogen Recombinant Protein Location Secreted, Endosome, Cell membrane, Endoplasmic reticulum Accession P17693 Clone Number S 2711 78 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample SK OV 3, U937, Jurkat, JEG 3 Purification Protein A Concentration

Product Specification


Host Rabbit
Antigen HLA-G
Synonyms HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; MHC class I antigen G; HLA-6.0; HLAG
Immunogen Recombinant Protein
Location Secreted, Endosome, Cell membrane, Endoplasmic reticulum
Accession P17693
Clone Number S-2711-78
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample SK-OV-3, U937, Jurkat, JEG-3
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:2000-1:10000 Hu

Background

HLA-G (human leukocyte antigen-G) is a non-classical, heavily glycosylated HLA class Ib molecule that is selectively expressed at the maternal-fetal interface (primarily on invading extravillous cytotrophoblasts) and in immune-privileged adult tissues, where it exerts potent tolerogenic functions through interaction with inhibitory receptors (ILT2, ILT4, KIR2DL4) on NK cells, T cells, macrophages and dendritic cells, thereby inhibiting cytotoxicity, proliferation and cytokine production, promoting regulatory T-cell generation, and ultimately contributing to immune evasion by tumors, acceptance of semi-allogeneic fetuses, and survival of transplanted grafts; its surface expression can be generated through alternative splicing of seven reported isoforms (HLA-G1 to -G7), with HLA-G1 being the full-length membrane-bound form that can also be proteolytically cleaved to generate soluble HLA-G5, while the other isoforms are either soluble or anchored via glycolipid, and its expression is tightly regulated by genetically polymorphic 5′-upstream regulatory elements, hypoxia, cytokines (IL-10, IFN-β, GM-CSF), and microRNAs, making HLA-G a key diagnostic, prognostic and therapeutic target in pregnancy complications, transplantation, autoimmunity and cancer.

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SKU: 50453321647

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Richard T. Russell
Battle Creek, US
★★★★★ 5
A Difficult to Find T-Shirt
These T-Shirts are nice. A super difficult to find. The manufacturer calls it a mock-turtle neck (MTN). But the collar height is actually a bit shorter than the traditional MTN, which is great. It's closer to a regular T-Shirt that comes all the way to the neckline. And very somt a comfortable. This is the perfect style of T-Shirt to wear under a sportscoat, if desired. Or under a shirt where you want the T-Shirt to show for contrast. Just the right look.
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Reviewed in the United States on February 17, 2026
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Dario Escobar
Charlottesville, US
★★★★★ 1
Sugerencia
Me llego pero el pedido tiene un fuerte mal olor a agua tipo de químico que aún lavandolo no se se va el mal olor . primera ves que me pasa esto
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Reviewed in the United States on March 7, 2026
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katherine
Los Angeles, US
★★★★★ 4
Nice shirts for the price! But do not recommend for thick body types.
I bought 3 different ones. 2 Mediums and 1 2XL. The mediums fit correct and really nice! Would definitely recommend for the price! More like a exercise material, and sticks to your body shape... Sooo the 2Xl did not fit the person correct. Was so tight... And the strech is to stick to your body... So would not recommend for anyone a bit hefty or fit tbh. But the shirts are good materials and feel nice for a fresh day out or to use as gym clothes!!
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Reviewed in the United States on August 26, 2025
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Liliana Fernandez
Houston, US
★★★★★ 5
Great Value heat gear material with high neck collar and loose fitting
Color: Black, Size: X-Large
My husband has been looking for mock neck shirts that are comparable to UA heat gear material but that are short sleeve and fit loose to wear under his work uniform. These seemed to have been a good soft quality option and the price is is great.
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Reviewed in the United States on December 4, 2025
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Verified Purchase
My boots has not arrived yet,however I have been ordering these boots for the second time.They are comfortable for winter I work on delivery
Chelsea, US
★★★★★ 5
Bought second one
Color: Navy, Size: Medium
I bought the black T-shirt about a month ago and really liked the quality the fabric is soft, the fit is great, and it holds up well after washing. So I decided to get the same one in dark blue.Very satisfied with the purchase
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Reviewed in the United States on December 9, 2025

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