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Ships within 48 hours · Estimated delivery Jul 7 - Jul 12
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Description
Human Apolipoprotein E/APOE Serum & Plasma Onestep ELISA KitProduct Specification Antigen Apolipoprotein E APOE Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 2. 8% Inter assay: 4. 1% Sample type Serum, Plasma Assay type Sandwich (quantitative) Sensitivity 0. 482 ng mL Range 0. 625 ng mL 40 ng mL Recovery Serum: 101% Plasma: 104% Assay time 60
Product Specification
| Antigen | Apolipoprotein E/APOE |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 2.8%； Inter-assay: 4.1% |
| Sample type | Serum, Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.482 ng/mL |
| Range | 0.625 ng/mL – 40 ng/mL |
| Recovery | Serum: 101% Plasma: 104% |
| Assay time | 60 minutes |
| Species reactivity | Hu |
Background
Human APOE (Apolipoprotein E) is a key protein involved in lipid metabolism, primarily produced in the liver and brain. It functions as a carrier for cholesterol and other fats, facilitating their transport through the bloodstream. APOE exists in three common isoforms—APOE2, APOE3, and APOE4—which differ by single amino acids. Among these, APOE4 is the strongest genetic risk factor for late-onset Alzheimer's disease, while APOE2 appears to offer some protective effects. The protein also plays a crucial role in neuronal repair and inflammation regulation within the central nervous system. Its interaction with cellular receptors allows cells to take up lipids for membrane maintenance and energy. Overall, APOE is essential for both cardiovascular and brain health, with its genetic variations significantly influencing disease susceptibility.
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